HDAC1 Antibody - N-terminal region : FITC (ARP38529_P050-FITC)
Selected Variant
ARP38529_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Histone deacetylase 1
Gene Aliases
HD1, RPD3, KDAC1, GON-10, RPD3L1
Gene ID
3065
Swiss Prot
Q13547
Accession Number
NP_004955
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human HDAC1
Target
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Partner Proteins
BCL6; CUL4B; YY1; SIN3A; RCOR1; KDM1A; KAT5; NCOR2; SUMO1; DDIT3; DDB1; BCOR; SF3A1; TP53; SP1; SUMO2; NFKB1; NFE2L2; MDM2; SMAD3; SMAD1; JUN; CHFR; HIF1A; HDAC2; EP300; SAP130; UBC; RELA; RB1; RARA; PRDM6; HAUS2; FEZF2; BANP; WHSC1; ESR1; DNMT3B; DNMT1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
55kDa
Shipping Conditions
Wet Ice
Protein Length
482
NCBI Gene Symbol
HDAC1
NCBI GB Accession Number
HDAC1
Host or Source
Rabbit
Protein Name
Histone deacetylase 1
Nucleotide Accession Number
NM_004964
Peptide Sequence
CYYYDGDVGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKANA
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