SF1 Antibody - N-terminal region : Biotin (ARP38504_P050-Biotin)
Product Specifications
Gene Name
Splicing factor 1
Gene Aliases
BBP, MBBP, ZFM1, ZNF162, D11S636, ZCCHC25
Gene ID
7536
Swiss Prot
Q15637
Accession Number
NP_004621
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human SF1
Target
SF1 contains 1 CCHC-type zinc finger and 1 KH domain. SF1 is Necessary for the ATP-dependent first step of spliceosome assembly. It binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. SF1 may act as transcription repressor.
Partner Proteins
KRTAP26-1; TRIM69; FAM168A; CIAO1; MKRN3; PSMA3; FUS; UBC; NEDD8; SUZ12; EED; RPL24; PLOD2; OSBP; NARS; GFPT1; GART; EIF4B; APBB1; SUPT5H; TROVE2; ITCH; PRPF40A; SAMHD1; XPO7; WBP4; FAF1; TCERG1; HSPH1; FARSB; GAS7; RANBP3; HIRIP3; HIST1H4A; XRCC5; U2AF2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 75%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
68kDa
References & Citations
Rino, J., (2008) Mol. Cell. Biol. 28 (9), 3045-3057
Shipping Conditions
Wet Ice
Protein Length
639
NCBI Gene Symbol
SF1
NCBI GB Accession Number
SF1
Host or Source
Rabbit
Protein Name
Splicing factor 1
Nucleotide Accession Number
NM_004630
Peptide Sequence
ATGANATPLDFPSKKRKRSRWNQDTMEQKTVIPGMPTVIPPGLTREQERA
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