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MLLT3 Antibody - C-terminal region : HRP (ARP38490_P050-HRP)

Selected Variant

ARP38490_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) ; translocated to, 3

Gene Aliases

AF9, YEATS3

Gene ID

4300

Swiss Prot

Q6LEQ8

Accession Number

BAA04090

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human MLLT3

Target

MLLT3 is a regulator of early erythroid and megakaryocytic cell fate in the human system. Expression of MLLT3 in human CD34+ cells induces acute myeloid, lymphoid, or mixed-lineage leukemia in immunodeficient mice. Translocation t (9;11) (p22; q23), a chromosomal aberration involving MLLT3 is associated with acute leukemias.

Partner Proteins

CDK9; HSP90B1; EAF1; AFF4; ELL2; MED26; ELL; MLLT3; AFF1; MLLT1; CDK6; CCNT1; CCNT2; APP; Cbx8; DOT1L; PAF1; KMT2A; BCOR; MLLT10; RNF2; AFF3; EEF2; ACACA; PCGF1; ELL3; NIPBL; SIRT1; LRIF1; RBM48; APPBP2; MCM6; PTN; EEF1A1; SGK1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

MLLT3 is strongly supported by BioGPS gene expression data to be expressed in 721_B MLLT3 is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

37kDa

Shipping Conditions

Wet Ice

Protein Length

342

NCBI Gene Symbol

MLLT3

NCBI GB Accession Number

MLLT3

Host or Source

Rabbit

Protein Name

LTG9/MLLT3 protein EMBL BAA04090.1

Nucleotide Accession Number

NM_004529

Peptide Sequence

ERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS

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