MLLT3 Antibody - C-terminal region : Biotin (ARP38490_P050-Biotin)
Product Specifications
Gene Name
Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) ; translocated to, 3
Gene Aliases
AF9, YEATS3
Gene ID
4300
Swiss Prot
Q6LEQ8
Accession Number
BAA04090
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human MLLT3
Target
MLLT3 is a regulator of early erythroid and megakaryocytic cell fate in the human system. Expression of MLLT3 in human CD34+ cells induces acute myeloid, lymphoid, or mixed-lineage leukemia in immunodeficient mice. Translocation t (9;11) (p22; q23), a chromosomal aberration involving MLLT3 is associated with acute leukemias.
Partner Proteins
CDK9; HSP90B1; EAF1; AFF4; ELL2; MED26; ELL; MLLT3; AFF1; MLLT1; CDK6; CCNT1; CCNT2; APP; Cbx8; DOT1L; PAF1; KMT2A; BCOR; MLLT10; RNF2; AFF3; EEF2; ACACA; PCGF1; ELL3; NIPBL; SIRT1; LRIF1; RBM48; APPBP2; MCM6; PTN; EEF1A1; SGK1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
MLLT3 is strongly supported by BioGPS gene expression data to be expressed in 721_B MLLT3 is supported by BioGPS gene expression data to be expressed in HeLa
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
37kDa
Shipping Conditions
Wet Ice
Protein Length
342
NCBI Gene Symbol
MLLT3
NCBI GB Accession Number
MLLT3
Host or Source
Rabbit
Protein Name
LTG9/MLLT3 protein EMBL BAA04090.1
Nucleotide Accession Number
NM_004529
Peptide Sequence
ERHILQQIVNLIEETGHFHITNTTFDFDLCSLDKTTVRKLQSYLETSGTS
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