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MLLT3 Antibody - N-terminal region : HRP (ARP38489_P050-HRP)

Selected Variant

ARP38489_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) ; translocated to, 3

Gene Aliases

AF9, YEATS3

Gene ID

4300

Swiss Prot

P42568

Accession Number

NP_004520

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MLLT3

Target

MLLT3 is a regulator of early erythroid and megakaryocytic cell fate in the human system. Expression of MLLT3 in human CD34+ cells induces acute myeloid, lymphoid, or mixed-lineage leukemia in immunodeficient mice. Translocation t (9;11) (p22; q23), a chromosomal aberration involving MLLT3 is associated with acute leukemias.

Partner Proteins

CDK9; HSP90B1; EAF1; AFF4; ELL2; MED26; ELL; MLLT3; AFF1; MLLT1; CDK6; CCNT1; CCNT2; APP; Cbx8; DOT1L; PAF1; KMT2A; BCOR; MLLT10; RNF2; AFF3; EEF2; ACACA; PCGF1; ELL3; NIPBL; SIRT1; LRIF1; RBM48; APPBP2; MCM6; PTN; EEF1A1; SGK1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

MLLT3 is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 86%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

63kDa

References & Citations

Wei, J., (2008) Cancer Cell 13 (6), 483-495

Shipping Conditions

Wet Ice

Protein Length

568

NCBI Gene Symbol

MLLT3

NCBI GB Accession Number

MLLT3

Host or Source

Rabbit

Protein Name

Protein AF-9

Nucleotide Accession Number

NM_004529

Peptide Sequence

MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEK

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