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MLLT3 Antibody - N-terminal region : Biotin (ARP38489_P050-Biotin)

Product Specifications

Gene Name

Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) ; translocated to, 3

Gene Aliases

AF9, YEATS3

Gene ID

4300

Swiss Prot

P42568

Accession Number

NP_004520

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MLLT3

Target

MLLT3 is a regulator of early erythroid and megakaryocytic cell fate in the human system. Expression of MLLT3 in human CD34+ cells induces acute myeloid, lymphoid, or mixed-lineage leukemia in immunodeficient mice. Translocation t (9;11) (p22; q23), a chromosomal aberration involving MLLT3 is associated with acute leukemias.

Partner Proteins

CDK9; HSP90B1; EAF1; AFF4; ELL2; MED26; ELL; MLLT3; AFF1; MLLT1; CDK6; CCNT1; CCNT2; APP; Cbx8; DOT1L; PAF1; KMT2A; BCOR; MLLT10; RNF2; AFF3; EEF2; ACACA; PCGF1; ELL3; NIPBL; SIRT1; LRIF1; RBM48; APPBP2; MCM6; PTN; EEF1A1; SGK1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

MLLT3 is supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 86%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

63kDa

References & Citations

Wei, J., (2008) Cancer Cell 13 (6), 483-495

Shipping Conditions

Wet Ice

Protein Length

568

NCBI Gene Symbol

MLLT3

NCBI GB Accession Number

MLLT3

Host or Source

Rabbit

Protein Name

Protein AF-9

Nucleotide Accession Number

NM_004529

Peptide Sequence

MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEK

Frequently Asked Questions

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