ONECUT1 Antibody - middle region : Biotin (ARP38481_P050-Biotin)
Selected Variant
ARP38481_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
One cut homeobox 1
Gene Aliases
HNF6, HNF-6, HNF6A
Gene ID
3175
Swiss Prot
Q9UBC0
Accession Number
NP_004489
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ONECUT1
Target
ONECUT1 belongs to the CUT homeobox family. It contains 1 CUT DNA-binding domain and 1 homeobox DNA-binding domain. It is a transcriptional activator. ONECUT1 binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.
Partner Proteins
NR0B2; KAT2B; FOXA2; CREBBP; NR3C1; FOXA1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
51kDa
References & Citations
Jiang, X., (2008) Oncol. Rep. 19 (1), 157-163
Shipping Conditions
Wet Ice
Protein Length
465
NCBI Gene Symbol
ONECUT1
NCBI GB Accession Number
ONECUT1
Host or Source
Rabbit
Protein Name
Hepatocyte nuclear factor 6
Nucleotide Accession Number
NM_004498
Peptide Sequence
ITISQQLGLELSTVSNFFMNARRRSLDKWQDEGSSNSGNSSSSSSTCTKA
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