ONECUT1 Antibody - middle region: Biotin (ARP38481_P050-Biotin)
Product Specifications
Gene Name
One cut homeobox 1
Gene Aliases
HNF6, HNF-6, HNF6A
Gene ID
3175
Swiss Prot
Q9UBC0
Accession Number
NP_004489
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human ONECUT1
Target
ONECUT1 belongs to the CUT homeobox family. It contains 1 CUT DNA-binding domain and 1 homeobox DNA-binding domain. It is a transcriptional activator. ONECUT1 binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.
Partner Proteins
NR0B2; KAT2B; FOXA2; CREBBP; NR3C1; FOXA1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 93%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
51kDa
Shipping Conditions
Wet Ice
Protein Length
465
NCBI Gene Symbol
ONECUT1
Protein Name
Hepatocyte nuclear factor 6
Nucleotide Accession Number
NM_004498
Curated Selection
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