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ONECUT1 Antibody - N-terminal region : HRP (ARP38480_P050-HRP)

Selected Variant

ARP38480_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

One cut homeobox 1

Gene Aliases

HNF6, HNF-6, HNF6A

Gene ID

3175

Swiss Prot

Q9UBC0

Accession Number

NP_004489

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ONECUT1

Target

ONECUT1 belongs to the CUT homeobox family. It contains 1 CUT DNA-binding domain and 1 homeobox DNA-binding domain. It is a transcriptional activator. ONECUT1 binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR. It is important for liver genes transcription.

Partner Proteins

NR0B2; KAT2B; FOXA2; CREBBP; NR3C1; FOXA1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 86%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

51kDa

References & Citations

Jiang, X., (2008) Oncol. Rep. 19 (1), 157-163

Shipping Conditions

Wet Ice

Protein Length

465

NCBI Gene Symbol

ONECUT1

NCBI GB Accession Number

ONECUT1

Host or Source

Rabbit

Protein Name

Hepatocyte nuclear factor 6

Nucleotide Accession Number

NM_004498

Peptide Sequence

NAQLTMEAIGELHGVSHEPVPAPADLLGGSPHARSSVAHRGSHLPPAHPR

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