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DTX1 Antibody - N-terminal region : HRP (ARP38458_P050-HRP)

Selected Variant

ARP38458_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Deltex homolog 1 (Drosophila)

Gene Aliases

HDx-1, RNF140

Gene ID

1840

Swiss Prot

Q86Y01

Accession Number

NP_004407

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DTX1

Target

Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity.

Partner Proteins

TAX1BP3; G3BP1; DEFA5; EGR2; UBC; ITCH; EIF3F; NOTCH1; MAP3K1; UBE2U; UBE2D4; UBE2C; UBE2N; UBE2E1; UBE2D3; UBE2D2; UBE2D1; DTX3L; DTX3; DTX2; EP300; DTX1; NOTCH2; GRB2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

67kDa

References & Citations

Takeyama, K., (2003) J. Biol. Chem. 278 (24), 21930-21937

Shipping Conditions

Wet Ice

Protein Length

620

NCBI Gene Symbol

DTX1

NCBI GB Accession Number

DTX1

Host or Source

Rabbit

Protein Name

E3 ubiquitin-protein ligase DTX1

Nucleotide Accession Number

NM_004416

Peptide Sequence

SRWRPYTATVCHHIENVLKEDARGSVVLGQVDAQLVPYIIDLQSMHQFRQ

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