TRIP13 Antibody - C-terminal region: FITC (ARP38434_T100-FITC)
Product Specifications
Gene Name
Thyroid hormone receptor interactor 13
Gene Aliases
MVA3, OOMD9, 16E1BP
Gene ID
9319
Swiss Prot
Q15645
Accession Number
NP_004228
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human TRIP13
Target
The thyroid hormone (T3) receptors (TRs) are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. TRIP13 specifically interacts with the ligand binding domain of the TRs. It is a member of Trips (TR-interacting proteins) family. Nearly all of the Trips also show similar ligand-dependent interaction with the retinoid X receptor (RXR), but none interact with the glucocorticoid receptor under any conditions. Trips predict specific functional roles: one is an apparent human homolog of a yeast transcriptional coactivator, one is a new member of a class of nonhistone chromosomal proteins, and one contains a conserved domain associated with ubiquitination of specific target proteins.
Partner Proteins
KRTAP26-1; KRTAP12-1; KRTAP12-2; MORN3; TEX37; METTL15; MGAT5B; C4orf33; GLYCTK; M1AP; LRR1; LNX1; RHOXF2; LOXL4; ZNF34; FNDC3B; TINAGL1; PBLD; SEMA4G; SPRYD7; PELI1; PLSCR3; PCMTD2; CYB5R2; AMDHD2; TNRC6A; DIP2A; DPYSL4; TRIP13; SIGLEC5; TPT1; SCP2; QARS
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Sample Type
TRIP13 is supported by BioGPS gene expression data to be expressed in HepG2
Concentration
0.5 mg/mL
Homology
Cow: 91%; Dog: 100%; Guinea Pig: 82%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
49kDa
Shipping Conditions
Wet Ice
Protein Length
432
NCBI Gene Symbol
TRIP13
Protein Name
Pachytene checkpoint protein 2 homolog
Nucleotide Accession Number
NM_004237
Curated Selection
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