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TRIP13 Antibody - C-terminal region: FITC (ARP38434_T100-FITC)

Product Specifications

Gene Name

Thyroid hormone receptor interactor 13

Gene Aliases

MVA3, OOMD9, 16E1BP

Gene ID

9319

Swiss Prot

Q15645

Accession Number

NP_004228

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human TRIP13

Target

The thyroid hormone (T3) receptors (TRs) are hormone-dependent transcription factors that regulate expression of a variety of specific target genes. TRIP13 specifically interacts with the ligand binding domain of the TRs. It is a member of Trips (TR-interacting proteins) family. Nearly all of the Trips also show similar ligand-dependent interaction with the retinoid X receptor (RXR), but none interact with the glucocorticoid receptor under any conditions. Trips predict specific functional roles: one is an apparent human homolog of a yeast transcriptional coactivator, one is a new member of a class of nonhistone chromosomal proteins, and one contains a conserved domain associated with ubiquitination of specific target proteins.

Partner Proteins

KRTAP26-1; KRTAP12-1; KRTAP12-2; MORN3; TEX37; METTL15; MGAT5B; C4orf33; GLYCTK; M1AP; LRR1; LNX1; RHOXF2; LOXL4; ZNF34; FNDC3B; TINAGL1; PBLD; SEMA4G; SPRYD7; PELI1; PLSCR3; PCMTD2; CYB5R2; AMDHD2; TNRC6A; DIP2A; DPYSL4; TRIP13; SIGLEC5; TPT1; SCP2; QARS

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

TRIP13 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/mL

Homology

Cow: 91%; Dog: 100%; Guinea Pig: 82%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

49kDa

Shipping Conditions

Wet Ice

Protein Length

432

NCBI Gene Symbol

TRIP13

Protein Name

Pachytene checkpoint protein 2 homolog

Nucleotide Accession Number

NM_004237

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