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KLF4 Antibody - C-terminal region : HRP (ARP38430_P050-HRP)

Product Specifications

Gene Name

Kruppel-like factor 4 (gut)

Gene Aliases

EZF, GKLF

Gene ID

9314

Swiss Prot

O43474

Accession Number

NP_004226

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human KLF4

Target

The mammalian Kruppel-like transcription factor, KLF4 is involved in preventing centrosome amplification following DNA damage caused by gamma-irradiation. It is both necessary and sufficient in preventing centrosome amplification following gamma-radiation-induced DNA damage and does so by transcriptionally suppressing cyclin E expression n. Kruppel-like factor 4 is also known to exhibit checkpoint function during the G1/S and G2/M transitions of the cell cycle.

Partner Proteins

EP300; CREBBP; SETD7; CTBP1; Dlg4; APP; CUL2; VHL; UBC; TCEB2; SP1; RELA; PRKCD; PPARG; SMARCA4; HDAC2; HDAC7; KAT5; HDAC1; HDAC5; ELK1; KLF6; TP53

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

50kDa

References & Citations

Natesampillai, S., Am. J. Physiol. Endocrinol. Metab. 294 (2), E385-E391 (2008)

Shipping Conditions

Wet Ice

Protein Length

470

NCBI Gene Symbol

KLF4

NCBI GB Accession Number

KLF4

Host or Source

Rabbit

Protein Name

Krueppel-like factor 4

Nucleotide Accession Number

NM_004235

Peptide Sequence

AGCGKTYTKSSHLKAHLRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKH

Frequently Asked Questions

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