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IRF7 Antibody - N-terminal region : Biotin (ARP38414_P050-Biotin)

Product Specifications

Gene Name

Interferon regulatory factor 7

Gene Aliases

IMD39, IRF-7, IRF7A, IRF7B, IRF7C, IRF7H, IRF-7H

Gene ID

3665

Swiss Prot

Q92985-3

Accession Number

NP_004022

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human IRF7

Target

IRF7 is interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue.IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. Inducible expression of IRF7 is largely restricted to lymphoid tissue. Multiple IRF7 transcript variants have been identified, although the functional consequences of these have not yet been established.

Partner Proteins

UBC; SUMO2; SUMO3; TRAF6; NMI; DEAF1; MAFB; SMAD4; SMAD3; SMAD2; vIRF-1; Dlg4; PIAS4; INSR; GCLM; ACADS; MAVS; IRF7; IRF3; IRAK1; TBK1; TRIM28; SUMO1; EP300; CREBBP; TNFAIP3; TRIM21; P4HA1; ARAF; Gbp4; HACE1; CCDC47; TRMT61B; PALD1; TRMT2A; LTN1; TLK2; IQ

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

IRF7 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 93%; Horse: 79%; Human: 100%; Mouse: 79%; Pig: 93%; Rabbit: 93%; Rat: 93%; Zebrafish: 75%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

18kDa

References & Citations

Sermasathanasawadi, R., (er) Liver Int. (2008) In press

Shipping Conditions

Wet Ice

Protein Length

164

NCBI Gene Symbol

IRF7

NCBI GB Accession Number

IRF7

Host or Source

Rabbit

Protein Name

Interferon regulatory factor 7

Nucleotide Accession Number

NM_004031

Peptide Sequence

ISSGCYEGLQWLDEARTCFRVPWKHFARKDLSEADARIFKAWAVARGRWP

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