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ZPR1 Antibody - N-terminal region : Biotin (ARP38399_P050-Biotin)

Product Specifications

Gene Name

ZPR1 zinc finger

Gene Aliases

ZNF259

Gene ID

8882

Swiss Prot

O75312

Accession Number

NP_003895

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF259

Target

The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

UBC; P3H1; FKBP10; RPRD1B; OSGEP; PPME1; SZRD1; ARIH1; HSPBP1; ACTR2; ACTR3; ARPC4; UBA2; TOM1L1; OGT; SURF2; PPP1R7; LPP; HSF1; AGFG1; HNRNPF; BAG1; ALAD; MPP3; SRXN1; NUDCD2; UBL7; THOC7; KLC2; UBQLN4; UFM1; UFC1; UBXN1; UHRF1; PHPT1; TES; UBXN7; HYPK

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

ZNF259 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

51kDa

References & Citations

Gangwani, L., et al., (2005) Mol. Cell. Biol. 25 (7), 2744-2756

Shipping Conditions

Wet Ice

Protein Length

459

NCBI Gene Symbol

ZPR1

NCBI GB Accession Number

ZPR1

Host or Source

Rabbit

Protein Name

Zinc finger protein ZPR1

Nucleotide Accession Number

NM_003904

Peptide Sequence

PPGAAVAPSPAPAPPPAPDHLFRPISAEDEEQQPTEIESLCMNCYCNGMT

Frequently Asked Questions

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