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CREG1 Antibody - N-terminal region : HRP (ARP38388_P050-HRP)

Selected Variant

ARP38388_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Cellular repressor of E1A-stimulated genes 1

Gene Aliases

CREG

Gene ID

8804

Swiss Prot

O75629

Accession Number

NP_003842

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CREG1

Target

The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. CREG1 antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro.The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.

Partner Proteins

FBXO6; CAPN1; TBP; RBL2; RB1; IGF2R; RBL1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

24kDa

References & Citations

Sacher, M., (2005) Proc. Natl. Acad. Sci. U.S.A. 102 (51), 18326-18331

Shipping Conditions

Wet Ice

Protein Length

220

NCBI Gene Symbol

CREG1

NCBI GB Accession Number

CREG1

Host or Source

Rabbit

Protein Name

Protein CREG1

Nucleotide Accession Number

NM_003851

Peptide Sequence

MAGLSRGSARALLAALLASTLLALLVSPARGRGGRDHGDWDEASRLPPLP

Price

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