NR5A2 Antibody - N-terminal region : FITC (ARP38386_T100-FITC)
Selected Variant
ARP38386_T100-FITC
Size: 100 µL
Product Specifications
Gene Name
Nuclear receptor subfamily 5, group A, member 2
Gene Aliases
B1F, CPF, FTF, B1F2, LRH1, LRH-1, FTZ-F1, hB1F-2, FTZ-F1beta
Gene ID
2494
Swiss Prot
O00482
Accession Number
NP_995582
Host
Rabbit
Reactivity
Human, Rat, Cow, Guinea Pig, Pig, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human NR5A2
Target
NR5A2 binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. It may be responsable for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. It is a key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. It may also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
Partner Proteins
NSD1; NCOA1; CREB1; UBE2I; RAD54L2; NR0B2; GPS2; ILF3; PNRC2; COPS5; PNRC1; BCKDK; NRIP1; SRC; NPPA; FTH1; ALB; SUMO1; PPARGC1A; POLR2D; EDF1; SMARCD3; PROX1; Ncoa3; Ptpn6; CTNNB1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/ml
Homology
Cow: 100%; Guinea Pig: 86%; Human: 100%; Pig: 92%; Rat: 93%; Sheep: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
61kDa
References & Citations
Lee, Y.K., (2006) J. Biol. Chem. 281 (12), 7850-7855
Shipping Conditions
Wet Ice
Protein Length
541
NCBI Gene Symbol
NR5A2
NCBI GB Accession Number
NR5A2
Host or Source
Rabbit
Protein Name
Nuclear receptor subfamily 5 group A member 2
Nucleotide Accession Number
NM_205860
Peptide Sequence
MSSNSDTGDLQESLKHGLTPIVSQFKMVNYSYDEDLEELCPVCGDKVSGY
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