SMARCA5 Antibody - N-terminal region : Biotin (ARP38368_P050-Biotin)
Product Specifications
Gene Name
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
Gene Aliases
ISWI, SNF2H, hISWI, hSNF2H, WCRF135
Gene ID
8467
Swiss Prot
O60264
Accession Number
NP_003592
Host
Rabbit
Reactivity
Human, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human SMARCA5
Target
SMARCA5 is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA5 is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II.The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
SUMO2; SUMO3; HIST1H3A; UBC; RPA3; RPA2; RPA1; SUZ12; EED; RNF2; BMI1; HB-1; AT5G35210; LMNA; RSF1; BAZ1A; SMARCA5; WHSC1; SS18; SSX2; UL29; RNF168; VCP; NOTCH1; IK; HDAC2; HDAC1; CHRAC1; MBD3; PHGDH; NCSTN; POLR3A; RUVBL2; RBM14; SAP18; HNRNPR; EIF4A3; B
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Horse: 93%; Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
122kDa
References & Citations
Olsen, J.V., (2006) Cell 127 (3), 635-648
Shipping Conditions
Wet Ice
Protein Length
1052
NCBI Gene Symbol
SMARCA5
NCBI GB Accession Number
SMARCA5
Host or Source
Rabbit
Protein Name
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5
Nucleotide Accession Number
NM_003601
Peptide Sequence
SSAAEPPPPPPPESAPSKPAASIASGGSNSSNKGGPEGVAAQAVASAVSA
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