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YY1 Antibody - N-terminal region : HRP (ARP38301_P050-HRP)

Selected Variant

ARP38301_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

YY1 transcription factor

Gene Aliases

DELTA, NF-E1, UCRBP, GADEVS, INO80S, YIN-YANG-1

Gene ID

7528

Swiss Prot

P25490

Accession Number

NP_003394

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human YY1

Target

YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.YY1 is a ubiquitously distributed transcription factor belonging to the GLI-Kruppel class of zinc finger proteins. The protein is involved in repressing and activating a diverse number of promoters. YY1 may direct histone deacetylases and histone acetyltransferases to a promoter in order to activate or repress the promoter, thus implicating histone modification in the function of YY1.

Partner Proteins

HDAC1; SMURF2; UBC; SHFM1; RNF2; BMI1; SUZ12; RYBP; GABPB1; GABPA; PCGF2; RING1; EP300; LAMC2; SPRY1; SLC39A7; NR1H2; TESK1; RAF1; NFKB1; GRN; CRKL; ARRB1; SP1; WDHD1; ZNF24; NHP2L1; NCL; ZNF830; APP; ZNF638; EED; SMAD3; SMAD2; EZH2; SUMO1; SUMO3; INO80E

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that YY1 is expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 91%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Sheep: 93%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Mai, R.T., et al., (2006) Oncogene 25 (3), 448-462

Shipping Conditions

Wet Ice

Protein Length

414

NCBI Gene Symbol

YY1

NCBI GB Accession Number

YY1

Host or Source

Rabbit

Protein Name

Transcriptional repressor protein YY1

Nucleotide Accession Number

NM_003403

Peptide Sequence

MASGDTLYIATDGSEMPAEIVELHEIEVETIPVETIETTVVGEEEEEDDD

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