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NR2C2 Antibody - N-terminal region : Biotin (ARP38288_P050-Biotin)

Product Specifications

Gene Name

Nuclear receptor subfamily 2, group C, member 2

Gene Aliases

TR4, TAK1

Gene ID

7182

Swiss Prot

P49116

Accession Number

NP_003289

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NR2C2

Target

Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]) .[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

VPRBP; CUL4B; UBC; DDB1; KDM1A; NR2C2; HSP90AA1; JAZF1; TAB2; TRAF6; PELI1; PELI2; RBCK1; PDLIM7; TAB1; TRIM28; MTA1; HDAC3; NR2C1; RBBP4; HDAC1; DNMT1; CHD4; Cebpb; ITSN2; CD2AP; RXRB; NR2C2AP; PEBP1; HSP90AB1; CDC37; IKBKB; FKBP5; TRAF2; CHUK; HNF4A; AR

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 88%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 91%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

67kDa

References & Citations

Bouwmeester, T., (2004) Nat. Cell Biol. 6 (2), 97-105

Shipping Conditions

Wet Ice

Protein Length

615

NCBI Gene Symbol

NR2C2

NCBI GB Accession Number

NR2C2

Host or Source

Rabbit

Protein Name

Nuclear receptor subfamily 2 group C member 2

Nucleotide Accession Number

NM_003298

Peptide Sequence

FTSLNKEKIVTDQQTGQKIQIVTAVDASGSPKQQFILTSPDGAGTGKVIL

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