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TFAP2A Antibody - N-terminal region : FITC (ARP38281_P050-FITC)

Selected Variant

ARP38281_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)

Gene Aliases

AP-2, BOFS, AP2TF, TFAP2, AP-2alpha

Gene ID

7020

Swiss Prot

P05549

Accession Number

NP_003211

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human TFAP2A

Target

The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS) . Three transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

MKRN3; GSTO2; KCTD15; SUMO1; HECW2; SP1; BAG3; RB1; UBC; DAB2; Fcho2; EPAS1; SRA1; EPS15; KCTD1; EPN1; SH3BP4; UBE2I; AURKA; BRCA1; DNMT3A; ELAVL1; SUMO4; SUMO2; NPM1; YY1; PPARG; EPN2; CITED4; LDLRAP1; CITED2; EP300; MAGI1; WWP2; WWP1; HIP1; CASP6; CASP3

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 79%; Rat: 100%; Sheep: 92%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

48kDa

Shipping Conditions

Wet Ice

Protein Length

437

NCBI Gene Symbol

TFAP2A

NCBI GB Accession Number

TFAP2A

Host or Source

Rabbit

Protein Name

Transcription factor AP-2-alpha

Peptide Sequence

LWKLTDNIKYEDCEDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSHTPNA

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