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SUPT6H Antibody - N-terminal region : Biotin (ARP38260_T100-Biotin)

Product Specifications

Gene Name

Suppressor of Ty 6 homolog (S. cerevisiae)

Gene Aliases

SPT6, SPT6H, emb-5

Gene ID

6830

Swiss Prot

Q7KZ85

Accession Number

NP_003161

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SUPT6H

Target

SUPT6H may be functionally analogous to SPT6 and emb-5 and may therefore regulate transcription through establishment or maintenance of chromatin structure. Spt6 may also participates in the regulation of transcription by RNA polymerase II (RNAPII) . Human Spt6 (hSpt6) is a classic transcription elongation factor that enhances the rate of RNAPII elongation. HSpt6 is capable of stimulating transcription elongation both individually and in concert with DRB sensitivity-inducing factor (DSIF) .

Partner Proteins

CEP76; HAUS2; CEP250; TUBGCP3; CEP57; VCP; TUBG1; TP53; EMD; CDKN1A; UBC; EED; BMI1; POLR2C; ERBB2; CSNK2A1; BRCA1; MDC1; PAAF1; SIRT7; SUMO2; POLR2A; IWS1; WDR48; TCEA1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

SUPT6H is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Yeast: 77%; Zebrafish: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

199kDa

References & Citations

Endoh, M., et al., (2004) Mol. Cell. Biol. 24 (8), 3324-3336

Shipping Conditions

Wet Ice

Protein Length

1726

NCBI Gene Symbol

SUPT6H

NCBI GB Accession Number

SUPT6H

Host or Source

Rabbit

Protein Name

Transcription elongation factor SPT6

Nucleotide Accession Number

NM_003170

Peptide Sequence

EAEESEEEYNDEGEVVPRVTKKFVEEEDDDEEEEEENLDDQDEQGNLKGF

Frequently Asked Questions

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