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HLTF Antibody - N-terminal region : HRP (ARP38217_P050-HRP)

Selected Variant

ARP38217_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Helicase-like transcription factor

Gene Aliases

ZBU1, HLTF1, RNF80, HIP116, SNF2L3, HIP116A, SMARCA3

Gene ID

6596

Swiss Prot

Q14527

Accession Number

NP_003062

Host

Rabbit

Reactivity

Human, Mouse, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human HLTF

Target

SMARCA3 (HLTF) is a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SMARCA3 contains a RING finger DNA binding motif. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein.

Partner Proteins

CHFR; UBC; RAD18; SUMO2; RPA3; RPA2; RPA1; WBP4; BRCA1; DTL; SULT1C2; HSPA8; CDK9; NOTCH1; SP3; SP1; SPRTN; Cebpb; ELAVL1; Shprh; RNF146; tat; EWSR1; UBE2Z; RPAP1; USP7; EEF1G; UBE2V2; UBE2N; PCNA

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 77%; Pig: 100%; Rabbit: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

114kDa

References & Citations

Unk, I., (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (10), 3768-3773

Shipping Conditions

Wet Ice

Protein Length

1009

NCBI Gene Symbol

HLTF

NCBI GB Accession Number

HLTF

Host or Source

Rabbit

Protein Name

Helicase-like transcription factor

Nucleotide Accession Number

NM_003071

Peptide Sequence

SWMFKRDPVWKYLQTVQYGVHGNFPRLSYPTFFPRFEFQDVIPPDDFLTS

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