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RCV1 Antibody - C-terminal region : HRP (ARP38196_P050-HRP)

Selected Variant

ARP38196_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Recoverin

Gene Aliases

RCV1

Gene ID

5957

Swiss Prot

Q53XL0

Accession Number

NP_002894

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human RCV1

Target

RCV1 is a member of the recoverin family of neuronal calcium sensors. RCV1 contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.The protein encoded by this gene contains four calcium-binding EF-hand domains and belongs to the recoverin family of neuronal calcium sensors. Recoverin may prolong the termination of the phototransduction cascade by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy; an autoimmune disease of the retina caused by a tumor in another tissue.

Partner Proteins

GIT2; TGFBR2; SMAD3; IL15RA; TOP1; PQBP1; CAV1; GRK5; GRK6; GRK1; ADRBK1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 79%; Horse: 86%; Human: 100%; Pig: 75%; Rabbit: 79%; Rat: 85%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

23kDa

References & Citations

Miyagawa, Y., et al., (2003) Biochem. Biophys. Res. Commun. 300 (3), 669-673

Shipping Conditions

Wet Ice

Protein Length

200

NCBI Gene Symbol

RCVRN

NCBI GB Accession Number

RCVRN

Host or Source

Rabbit

Protein Name

Recoverin EMBL AAP88840.1

Nucleotide Accession Number

NM_002903

Peptide Sequence

KMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANK

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