RCV1 Antibody - C-terminal region : Biotin (ARP38196_P050-Biotin)
Product Specifications
Gene Name
Recoverin
Gene Aliases
RCV1
Gene ID
5957
Swiss Prot
Q53XL0
Accession Number
NP_002894
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human RCV1
Target
RCV1 is a member of the recoverin family of neuronal calcium sensors. RCV1 contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.The protein encoded by this gene contains four calcium-binding EF-hand domains and belongs to the recoverin family of neuronal calcium sensors. Recoverin may prolong the termination of the phototransduction cascade by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy; an autoimmune disease of the retina caused by a tumor in another tissue.
Partner Proteins
GIT2; TGFBR2; SMAD3; IL15RA; TOP1; PQBP1; CAV1; GRK5; GRK6; GRK1; ADRBK1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 79%; Horse: 86%; Human: 100%; Pig: 75%; Rabbit: 79%; Rat: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
23kDa
References & Citations
Miyagawa, Y., et al., (2003) Biochem. Biophys. Res. Commun. 300 (3), 669-673
Shipping Conditions
Wet Ice
Protein Length
200
NCBI Gene Symbol
RCVRN
NCBI GB Accession Number
RCVRN
Host or Source
Rabbit
Protein Name
Recoverin EMBL AAP88840.1
Nucleotide Accession Number
NM_002903
Peptide Sequence
KMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANK
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