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PSMC5 Antibody - C-terminal region: FITC (ARP38192_T100-FITC)

Product Specifications

Gene Name

Proteasome (prosome, macropain) 26S subunit, ATPase, 5

Gene Aliases

S8, p45, RPT6, SUG1, SUG-1, TBP10, TRIP1, p45/SUG

Gene ID

5705

Swiss Prot

P62195

Accession Number

NP_002796

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human PSMC5

Target

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.PSMC5 is one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha.

Partner Proteins

HUWE1; KRT38; KRT40; PDCL; CIITA; FOS; THAP11; SUMO2; SUMO3; Gabbr2; PSMD14; UBE3C; UBC; PSMB4; RPS13; RPL29; PSMD12; PSMD11; PSMD8; PSMD3; PSMD1; PSMC6; DYNC1I2; ABCF1; KCMF1; UCHL5; KIAA0368; UBR4; ADRM1; MAP2; PARK2; FBXO6; RORA; PSMC4; BAG3; HIV2gp7

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, IP, WB

Concentration

0.5 mg/mL

Homology

Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

46kDa

Shipping Conditions

Wet Ice

Protein Length

406

NCBI Gene Symbol

PSMC5

Protein Name

26S protease regulatory subunit 8

Nucleotide Accession Number

NM_002805

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