PSMC5 Antibody - C-terminal region: FITC (ARP38192_T100-FITC)
Product Specifications
Gene Name
Proteasome (prosome, macropain) 26S subunit, ATPase, 5
Gene Aliases
S8, p45, RPT6, SUG1, SUG-1, TBP10, TRIP1, p45/SUG
Gene ID
5705
Swiss Prot
P62195
Accession Number
NP_002796
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human PSMC5
Target
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.PSMC5 is one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha.
Partner Proteins
HUWE1; KRT38; KRT40; PDCL; CIITA; FOS; THAP11; SUMO2; SUMO3; Gabbr2; PSMD14; UBE3C; UBC; PSMB4; RPS13; RPL29; PSMD12; PSMD11; PSMD8; PSMD3; PSMD1; PSMC6; DYNC1I2; ABCF1; KCMF1; UCHL5; KIAA0368; UBR4; ADRM1; MAP2; PARK2; FBXO6; RORA; PSMC4; BAG3; HIV2gp7
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, IP, WB
Concentration
0.5 mg/mL
Homology
Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
46kDa
Shipping Conditions
Wet Ice
Protein Length
406
NCBI Gene Symbol
PSMC5
Protein Name
26S protease regulatory subunit 8
Nucleotide Accession Number
NM_002805
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items