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PLD2 Antibody - N-terminal region : HRP (ARP38182_P050-HRP)

Selected Variant

ARP38182_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Phospholipase D2

Gene Aliases

PLD1C

Gene ID

5338

Swiss Prot

O14939

Accession Number

NP_002654

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PLD2

Target

Phosphatidylcholine (PC) -specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.Phosphatidylcholine (PC) -specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-14 AF033850.1 61-74 15-614 BC015033.1 1-600 615-1279 BC056871.1 549-1213 1280-1830 BC015033.1 1266-1816 1831-1995 BC056871.1 1765-1929 1996-3489 BC015033.1 1982-3475

Partner Proteins

UBC; RPS6KB1; CUL3; AQP3; RPTOR; PEA15; PIP5K1A; STXBP1; DPYSL2; BIN1; MTOR; CAV1; AMPH; OPRM1; ALDOC; GM2A; PRKCD; PRKCA; PLCG1; LCK; GAPDH; FYN; EGFR; CSK; ALDOA; ARF1; ACTB; ACTN1; CAV2; SRC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 85%; Guinea Pig: 83%; Horse: 86%; Human: 100%; Mouse: 75%; Rabbit: 86%; Rat: 75%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

106kDa

References & Citations

Gorshkova, I., (2008) J. Biol. Chem. 283 (17), 11794-11806

Shipping Conditions

Wet Ice

Protein Length

933

NCBI Gene Symbol

PLD2

NCBI GB Accession Number

PLD2

Host or Source

Rabbit

Protein Name

Phospholipase D2

Nucleotide Accession Number

NM_002663

Peptide Sequence

MTATPESLFPTGDELDSSQLQMESDEVDTLKEGEDPADRMHPFLAIYELQ

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