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PBX2 Antibody - C-terminal region : HRP (ARP38173_T100-HRP)

Selected Variant

ARP38173_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

Pre-B-cell leukemia homeobox 2

Gene Aliases

G17, HOX12, PBX2MHC

Gene ID

5089

Swiss Prot

P40425

Accession Number

NP_002577

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human PBX2

Target

PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. PBX2 gene was identified by its similarity to a homeobox gene which is involved in t (1;19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter. This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t (1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.

Partner Proteins

CARD9; HOXA1; SOX2; ELAVL1; COPS6; ZDHHC7; SKIV2L2; SMYD3; MCRS1; CCDC88B; RPS6KC1; PBX2; PBX1; CENPBD1; DCTN3; NUP62; BAIAP2; IKBKAP; UBE2E1; PKNOX1; BLOC1S1; RPL4; HOXB8; HOXA9

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Sample Type

PBX2 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

46kDa

References & Citations

Lehner, B., et al., (2004) Genomics 83 (1), 153-167

Shipping Conditions

Wet Ice

Protein Length

430

NCBI Gene Symbol

PBX2

NCBI GB Accession Number

PBX2

Host or Source

Rabbit

Protein Name

Pre-B-cell leukemia transcription factor 2

Nucleotide Accession Number

NM_002586

Peptide Sequence

PGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEGPGSVHSDTSN

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