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PBX2 Antibody - N-terminal region : Biotin (ARP38172_P050-Biotin)

Selected Variant

ARP38172_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Pre-B-cell leukemia homeobox 2

Gene Aliases

G17, HOX12, PBX2MHC

Gene ID

5089

Swiss Prot

P40425

Accession Number

NP_002577

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PBX2

Target

PBX2 is a ubiquitously expressed member of the TALE/PBX homeobox family. PBX2 gene was identified by its similarity to a homeobox gene which is involved in t (1;19) translocation in acute pre-B-cell leukemias. PBX2 is a transcriptional activator which binds to the TLX1 promoter. This gene encodes a ubiquitously expressed member of the TALE/PBX homeobox family. It was identified by its similarity to a homeobox gene which is involved in t (1;19) translocation in acute pre-B-cell leukemias. This protein is a transcriptional activator which binds to the TLX1 promoter. The gene is located within the major histocompatibility complex (MHC) on chromosome 6.

Partner Proteins

CARD9; HOXA1; SOX2; ELAVL1; COPS6; ZDHHC7; SKIV2L2; SMYD3; MCRS1; CCDC88B; RPS6KC1; PBX2; PBX1; CENPBD1; DCTN3; NUP62; BAIAP2; IKBKAP; UBE2E1; PKNOX1; BLOC1S1; RPL4; HOXB8; HOXA9

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

There is BioGPS gene expression data showing that PBX2 is expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

46kDa

References & Citations

Lehner, B., et al., (2004) Genomics 83 (1), 153-167

Shipping Conditions

Wet Ice

Protein Length

430

NCBI Gene Symbol

PBX2

NCBI GB Accession Number

PBX2

Host or Source

Rabbit

Protein Name

Pre-B-cell leukemia transcription factor 2

Nucleotide Accession Number

NM_002586

Peptide Sequence

PGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQI

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