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NKX2-2 Antibody - N-terminal region : FITC (ARP38167_P050-FITC)

Selected Variant

ARP38167_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

NK2 homeobox 2

Gene Aliases

NKX2B, NKX2.2

Gene ID

4821

Swiss Prot

O95096

Accession Number

NP_002500

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NKX2-2

Target

Nkx2-2 contains 1 homeobox DNA-binding domain which is essential for interaction with OLIG2. Nkx2-2 may be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.

Partner Proteins

Dlg4; SIN3A; HDAC1; OLIG2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Sheep: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

30kDa

References & Citations

Owen, L.A., (er) PLoS ONE 3 (4), E1965 (2008)

Shipping Conditions

Wet Ice

Protein Length

273

NCBI Gene Symbol

NKX2-2

NCBI GB Accession Number

NKX2-2

Host or Source

Rabbit

Protein Name

Homeobox protein Nkx-2.2

Nucleotide Accession Number

NM_002509

Peptide Sequence

MSLTNTKTGFSVKDILDLPDTNDEEGSVAEGPEEENEGPEPAKRAGPLGQ

Price

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