IRF4 Antibody - middle region : Biotin (ARP38155_P050-Biotin)

Product Specifications

Gene Name

Interferon regulatory factor 4

Gene Aliases

MUM1, LSIRF, SHEP8, NF-EM5

Gene ID

3662

Swiss Prot

Q15306

Accession Number

NP_002451

Host

Rabbit

Reactivity

Human, Rat, Dog, Guinea Pig, Horse

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human IRF4

Target

IRF4 is a transcriptional activator. It binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter.It also binds the immunoglobulin lambda light chain enhancer, together with PU.1. IRF4 probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells.

Partner Proteins

UBC; STAT6; BCL6; TOP1; IRAK1; PRRC2B; YTHDC2; VPS35; PEG10; TLK2; CARM1; IKBKAP; ETV7; BATF; HOXB13; PROX1; HOXC11; FKBP4; SPIB; PRDM1; MYD88; TRAF2; NFATC2; SPI1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

IRF4 is strongly supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.