MSX2 Antibody - N-terminal region : Biotin (ARP38153_T100-Biotin)
Selected Variant
ARP38153_T100-Biotin
Size: 100 µL
Product Specifications
Gene Name
Msh homeobox 2
Gene Aliases
FPP, MSH, PFM, CRS2, HOX8, PFM1
Gene ID
4488
Swiss Prot
P35548
Accession Number
NP_002440
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MSX2
Target
MSX2 is a member of the muscle segment homeobox gene family. The protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
Partner Proteins
ATXN1; PIAS2; UBC; XRCC5; XRCC6; ZDHHC2; TLE2; TLE1; PPARG; POU2AF1; NR3C1; POLR3D; SPEN; ZBTB17; RUNX2; DLX5; MAGED1; GTF2F2; GTF2F1; MSX1; DLX2; MSX2; CEBPA; PITX2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Goat: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
29kDa
References & Citations
Le (2006) Calcif. Tissue Int. 78 (2), 98-102
Shipping Conditions
Wet Ice
Protein Length
267
NCBI Gene Symbol
MSX2
NCBI GB Accession Number
MSX2
Host or Source
Rabbit
Protein Name
Homeobox protein MSX-2
Nucleotide Accession Number
NM_002449
Peptide Sequence
MASPSKGNDLFSPDEEGPAVVAGPGPGPGGAEGAAEERRVKVSSLPFSVE
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