HMGB1 Antibody - N-terminal region : Biotin (ARP38109_P050-Biotin)
Product Specifications
Gene Name
High mobility group box 1
Gene Aliases
HMG1, HMG3, HMG-1, SBP-1
Gene ID
3146
Swiss Prot
P09429
Accession Number
NP_002119
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human HMGB1
Target
HMGB1 belongs to the HMGB family. It contains 2 HMG box DNA-binding domains. The protein binds preferentially single-stranded DNA and unwinds double stranded DNA. The oxidized HMGB1 may accumulate even in cells under oxidative stress.
Partner Proteins
AGTRAP; HUWE1; UBC; ASB2; ASB1; ZNF24; MAPK1; HMGA1; ITGA4; FN1; HNF1A; SSRP1; SMARCE1; PSEN1; XPC; XPA; RAD23B; CDK2; TFAP4; TERF2IP; TERF2; HHV8GK18_gp81; SUMO2; FCP1; DNM2; HSPA8; HMGB2; PDIA3; Ccdc15; POU5F1; H3F3A; CREBBP; CDK1; TBP; LRIF1; RASSF4; N
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Purification
Affinity Purified
Sample Type
HMGB1 is strongly supported by BioGPS gene expression data to be expressed in HeLa
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
25kDa
References & Citations
Straino, S., (2008) J. Invest. Dermatol. 128 (6), 1545-1553
Shipping Conditions
Wet Ice
Protein Length
215
NCBI Gene Symbol
HMGB1
NCBI GB Accession Number
HMGB1
Host or Source
Rabbit
Protein Name
High mobility group protein B1
Nucleotide Accession Number
NM_002128
Peptide Sequence
GKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKT
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