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PAX6 Antibody - C-terminal region : FITC (ARP38063_P050-FITC)

Selected Variant

ARP38063_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Paired box 6

Gene Aliases

AN, AN1, AN2, FVH1, MGDA, WAGR, ASGD5, D11S812E

Gene ID

5080

Swiss Prot

P26367

Accession Number

XP_005253013

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human PAX6

Target

This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Partner Proteins

IPO13; Dlg4; NKIRAS2; Cacnb3; Pax6; Diap1; SMAD5; SMAD4; SMAD3; SMAD1; AR; HIPK2; SUMO1; SMARCA4; TP73; SHANK3; PBX1; VSX2; EN1; TRIM11; HOMER3; SIX3; INADL; EP300; SOX10; RGS3; DIAPH1; MAFG; RAX; DYNLL1; DLG1; CDX2; TBP; SOX3; MITF; HOXB1; SOX2; LHX2; TA

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

46kDa

Shipping Conditions

Wet Ice

Protein Length

422

NCBI Gene Symbol

PAX6

NCBI GB Accession Number

PAX6

Host or Source

Rabbit

Protein Name

Paired box protein Pax-6

Peptide Sequence

PSVNGRSYDTYTPPHMQTHMNSQPMGTSGTTSTGLISPGVSVPVQVPGSE

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