FOXO3A Antibody - C-terminal region : Biotin (ARP38041_P050-Biotin)

Product Specifications

Gene Name

Forkhead box O3

Gene Aliases

FOXO2, AF6q21, FKHRL1, FOXO3A, FKHRL1P2

Gene ID

2309

Swiss Prot

Q68DV3

Accession Number

CAH18117

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human FOXO3A

Target

FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia.

Partner Proteins

SMAD3; YWHAB; ERBB2IP; SIRT1; YWHAE; CDK6; AKT1; IKBKB; CHUK; CDT1; UBC; SKP2; MAPK1; PCNA; MDM2; BTRC; CREBBP; ELAVL1; SMAD4; MAPK6; NR1H3; NR1H2; NLK; VDR; SMAD1; EP300; STK4; FANCD2; RAD17; MYC; H2AFX; BRCA1; ATM; SIRT3; ATG101; YWHAH; PGK1; GBAS; FKBP

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.