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PRDM1 Antibody - N-terminal region: Biotin (ARP38013_T100-Biotin)

Product Specifications

Gene Name

PR domain containing 1, with ZNF domain

Gene Aliases

BLIMP1, PRDI-BF1

Gene ID

639

Swiss Prot

O75626

Accession Number

NP_001189

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PRDM1

Target

PRDM1 is a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.

Partner Proteins

PRMT5; SENP1; EHMT2; PIAS1; SUMO1; IRF2; IRF1; HDAC2; HDAC1; HIST1H1A; MS4A1; HSP90AA1; ATXN1; ELAVL1; KDM1A; IRF4; TLE2; TLE1; AES; PRMT7; HIST2H3A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 83%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 92%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

88kDa

Shipping Conditions

Wet Ice

Protein Length

789

NCBI Gene Symbol

PRDM1

Protein Name

PR domain zinc finger protein 1

Nucleotide Accession Number

NM_001198

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