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PGR Antibody - N-terminal region : Biotin (ARP38005_P050-Biotin)

Product Specifications

Gene Name

Progesterone receptor

Gene Aliases

PR, NR3C3

Gene ID

5241

Swiss Prot

P06401

Accession Number

NP_000917

Host

Rabbit

Reactivity

Human, Rat

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PGR

Target

This protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy.This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

BCAS2; SRC; PGR; Dlg4; PARP1; ANP32A; XRCC5; PRKDC; XRCC6; MAGEA11; FKBP5; RBM23; RBM39; KAT2B; BRCA1; STUB1; DNAJC7; PPP5C; FKBP4; BPTF; CDK2; COPS5; NCOA1; UBC; ESR1; NCOA2; CCNA1; NCOA3; STAT3; SP1; Jdp2; Batf3; STAT5B; STAT5A; FGFR2; PRDM2; NCOR2; TAF

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

PGR is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Human: 100%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

99kDa

References & Citations

Onsory, K., Mol. Cell. Biochem. 314 (1-2), 25-35 (2008)

Shipping Conditions

Wet Ice

Protein Length

933

NCBI Gene Symbol

PGR

NCBI GB Accession Number

PGR

Host or Source

Rabbit

Protein Name

Progesterone receptor

Nucleotide Accession Number

NM_000926

Peptide Sequence

TELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAI

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