PGR Antibody - N-terminal region : Biotin (ARP38005_P050-Biotin)
Product Specifications
Gene Name
Progesterone receptor
Gene Aliases
PR, NR3C3
Gene ID
5241
Swiss Prot
P06401
Accession Number
NP_000917
Host
Rabbit
Reactivity
Human, Rat
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human PGR
Target
This protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy.This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
BCAS2; SRC; PGR; Dlg4; PARP1; ANP32A; XRCC5; PRKDC; XRCC6; MAGEA11; FKBP5; RBM23; RBM39; KAT2B; BRCA1; STUB1; DNAJC7; PPP5C; FKBP4; BPTF; CDK2; COPS5; NCOA1; UBC; ESR1; NCOA2; CCNA1; NCOA3; STAT3; SP1; Jdp2; Batf3; STAT5B; STAT5A; FGFR2; PRDM2; NCOR2; TAF
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
PGR is supported by BioGPS gene expression data to be expressed in 721_B
Concentration
0.5 mg/ml
Homology
Human: 100%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
99kDa
References & Citations
Onsory, K., Mol. Cell. Biochem. 314 (1-2), 25-35 (2008)
Shipping Conditions
Wet Ice
Protein Length
933
NCBI Gene Symbol
PGR
NCBI GB Accession Number
PGR
Host or Source
Rabbit
Protein Name
Progesterone receptor
Nucleotide Accession Number
NM_000926
Peptide Sequence
TELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAI
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