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RFX2 Antibody - middle region : Biotin (ARP38004_P050-Biotin)

Product Specifications

Gene Name

Regulatory factor X, 2 (influences HLA class II expression)

Gene Aliases

FLJ14226

Gene ID

5990

Swiss Prot

P48378

Accession Number

NP_000626

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RFX2

Target

RFX2 is a member of transcription factors that contain a highly-conserved winged helix DNA binding domain. RFX2 is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene.This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites.

Partner Proteins

RFX6; MDFI; RFX4; RFX1; RFX2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

80kDa

References & Citations

Horvath, G.C., (2004) Biol. Reprod. 71 (5), 1551-1559

Shipping Conditions

Wet Ice

Protein Length

723

NCBI Gene Symbol

RFX2

NCBI GB Accession Number

RFX2

Host or Source

Rabbit

Protein Name

DNA-binding protein RFX2

Nucleotide Accession Number

NM_000635

Peptide Sequence

NDLASLSLTLLDKDDMGDEQRGSEAGPDARSLGEPLVKRERSDPNHSLQG

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