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MEFV Antibody - N-terminal region : Biotin (ARP37973_P050-Biotin)

Product Specifications

Gene Name

Mediterranean fever

Gene Aliases

FMF, MEF, PAAND, TRIM20

Gene ID

4210

Swiss Prot

O15553

Accession Number

NP_000234

Host

Rabbit

Reactivity

Human, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MEFV

Target

MEFV was identified as the gene that when mutated causes Mediterranean fever, a hereditary periodic fever syndrome. MEFV is expressed in granulocytes and myeloid bone marrow precursors. This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

COG5; PYCARD; PSTPIP1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Horse: 85%; Human: 100%; Pig: 77%; Rabbit: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

86kDa

References & Citations

Gattorno, M., (2008) Arthritis Rheum. 58 (6), 1823-1832

Shipping Conditions

Wet Ice

Protein Length

781

NCBI Gene Symbol

MEFV

NCBI GB Accession Number

MEFV

Host or Source

Rabbit

Protein Name

Pyrin

Nucleotide Accession Number

NM_000243

Peptide Sequence

MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARP

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