MEFV Antibody - N-terminal region : Biotin (ARP37973_P050-Biotin)
Product Specifications
Gene Name
Mediterranean fever
Gene Aliases
FMF, MEF, PAAND, TRIM20
Gene ID
4210
Swiss Prot
O15553
Accession Number
NP_000234
Host
Rabbit
Reactivity
Human, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MEFV
Target
MEFV was identified as the gene that when mutated causes Mediterranean fever, a hereditary periodic fever syndrome. MEFV is expressed in granulocytes and myeloid bone marrow precursors. This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
COG5; PYCARD; PSTPIP1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Horse: 85%; Human: 100%; Pig: 77%; Rabbit: 77%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
86kDa
References & Citations
Gattorno, M., (2008) Arthritis Rheum. 58 (6), 1823-1832
Shipping Conditions
Wet Ice
Protein Length
781
NCBI Gene Symbol
MEFV
NCBI GB Accession Number
MEFV
Host or Source
Rabbit
Protein Name
Pyrin
Nucleotide Accession Number
NM_000243
Peptide Sequence
MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARP
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