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FBN1 Antibody - N-terminal region : Biotin (ARP37969_P050-Biotin)

Selected Variant

ARP37969_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Fibrillin 1

Gene Aliases

FBN, SGS, WMS, MASS, MFLS, MFS1, OCTD, SSKS, WMS2, ACMICD, ECTOL1, GPHYSD2

Gene ID

2200

Swiss Prot

Q75N89

Accession Number

BAD16737

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human FBN1

Target

FBN1 is a member of the fibrillin family. FBN1 is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome.

Partner Proteins

UBC; SPRY2; ATXN7; MYOC; MFAP5; MFAP2; LTBP1; HSPG2; FBLN2; ELN; DCN; FBN2; VCAN; CALR

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 79%; Pig: 93%; Rabbit: 100%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

21kDa

References & Citations

Uyeda, T., et al., (2004) J. Hum. Genet. 49 (8), 404-407

Shipping Conditions

Wet Ice

Protein Length

195

NCBI Gene Symbol

FBN1

NCBI GB Accession Number

FBN1

Host or Source

Rabbit

Protein Name

Fibrillin 1 EMBL BAD16737.1

Nucleotide Accession Number

NM_000138

Peptide Sequence

MRRGRLLEIALGFTVLLASYTSHGADANLEAGNVKETRASRAKRRGGGGH

Price

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