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ERCC6 Antibody - C-terminal region : FITC (ARP37966_P050-FITC)

Selected Variant

ARP37966_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Excision repair cross-complementation group 6

Gene Aliases

CSB, CKN2, COFS, ARMD5, COFS1, POF11, RAD26, UVSS1, CSB-PGBD3

Gene ID

2074

Swiss Prot

Q03468

Accession Number

NP_000115.1

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of human ERCC6

Target

This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Naturally-occurring readthrough transcription occurs between this gene and the adjacent PGBD3 gene (GeneID:267004), and results in a fusion protein that shares sequence with the product of each individual gene. The readthrough locus is represented by GeneID:101243544.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 79%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 79%; Rat: 86%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

94kDa

Shipping Conditions

Wet Ice

Protein Length

863

NCBI Gene Symbol

ERCC6

NCBI GB Accession Number

ERCC6

Host or Source

Rabbit

Protein Name

DNA excision repair protein ERCC-6

Nucleotide Accession Number

NM_000124.3

Peptide Sequence

EASALLPTTEHDDLLVEMRNFIAFQAHTDGQASTREILQEFESKLSASQS

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