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ERCC3 Antibody - N-terminal region : HRP (ARP37963_P050-HRP)

Selected Variant

ARP37963_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Excision repair cross-complementing rodent repair deficiency, complementation group 3

Gene Aliases

XPB, BTF2, Ssl2, TTD2, GTF2H, RAD25, TFIIH

Gene ID

2071

Swiss Prot

P19447

Accession Number

NP_000113

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ERCC3

Target

ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription.

Partner Proteins

XIAP; CEP70; UBC; rev; SRPK2; CDK7; TP53; E2F1; CDK8; CCNC; GTF2H5; ERCC2; MSANTD2; UVSSA; POLR2C; KPNA3; RAD52; MMS19; SIX5; GTF2H4; GTF2H3; GTF2H1; tat; COPS2; GTF2H2; NEDD8; ERCC6; POLR2A; AR; CCNH; MYC; MNAT1; ZSCAN1; ATF7IP; GCN1L1; ERCC5; BCR; PSMC5

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

ERCC3 is supported by BioGPS gene expression data to be expressed in HCT15

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 86%; Guinea Pig: 79%; Human: 100%; Pig: 93%; Rabbit: 79%; Rat: 79%; Yeast: 90%; Zebrafish: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

89kDa

Shipping Conditions

Wet Ice

Protein Length

782

NCBI Gene Symbol

ERCC3

NCBI GB Accession Number

ERCC3

Host or Source

Rabbit

Protein Name

TFIIH basal transcription factor complex helicase XPB subunit

Nucleotide Accession Number

NM_000122

Peptide Sequence

MGKRDRADRDKKKSRKRHYEDEEDDEEDAPGNDPQEAVPSAAGKQVDESG

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