ERCC3 Antibody - N-terminal region : Biotin (ARP37963_P050-Biotin)

Product Specifications

Gene Name

Excision repair cross-complementing rodent repair deficiency, complementation group 3

Gene Aliases

XPB, BTF2, Ssl2, TTD2, GTF2H, RAD25, TFIIH

Gene ID

2071

Swiss Prot

P19447

Accession Number

NP_000113

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ERCC3

Target

ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription.

Partner Proteins

XIAP; CEP70; UBC; rev; SRPK2; CDK7; TP53; E2F1; CDK8; CCNC; GTF2H5; ERCC2; MSANTD2; UVSSA; POLR2C; KPNA3; RAD52; MMS19; SIX5; GTF2H4; GTF2H3; GTF2H1; tat; COPS2; GTF2H2; NEDD8; ERCC6; POLR2A; AR; CCNH; MYC; MNAT1; ZSCAN1; ATF7IP; GCN1L1; ERCC5; BCR; PSMC5

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

ERCC3 is supported by BioGPS gene expression data to be expressed in HCT15

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 86%; Guinea Pig: 79%; Human: 100%; Pig: 93%; Rabbit: 79%; Rat: 79%; Yeast: 90%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.