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TGFB1 Antibody - middle region : Biotin (ARP37894_P050-Biotin)

Product Specifications

Gene Name

Transforming growth factor, beta 1

Gene Aliases

Tgfb, Tgfb-1, TGFbeta, TGF-beta, TGFbeta1, TGF-beta1

Gene ID

21803

Swiss Prot

P04202

Accession Number

NP_035707

Host

Rabbit

Reactivity

Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of mouse TGFB1

Target

Tgfb1 is a multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of them have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone remodelling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.

Partner Proteins

Htra1; Nrep; Ltbp3; Col1a1; Tgfbr3; Tgfbr1; Tgfbr2; Smad4; Hdac3; Jun

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB, IF

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 79%; Goat: 79%; Guinea Pig: 87%; Horse: 79%; Mouse: 100%; Pig: 93%; Rat: 93%; Sheep: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

43kDa

References & Citations

Cheon, S.S., (2006) FASEB J. 20 (6), 692-701

Shipping Conditions

Wet Ice

Protein Length

390

NCBI Gene Symbol

TGFB1

NCBI GB Accession Number

TGFB1

Host or Source

Rabbit

Protein Name

Transforming growth factor beta-1

Nucleotide Accession Number

NM_011577

Peptide Sequence

DTPEWLSFDVTGVVRQWLNQGDGIQGFRFSAHCSCDSKDNKLHVEINGIS

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