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ONECUT2 Antibody - N-terminal region : FITC (ARP37740_P050-FITC)

Product Specifications

Gene Name

One cut homeobox 2

Gene Aliases

OC2, OC-2

Gene ID

9480

Swiss Prot

O95948

Accession Number

NP_004843

Host

Rabbit

Reactivity

Human, Mouse, Rat, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ONECUT2

Target

ONECUT2 is a member of the transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF) -6. The distribution of OC-2 mRNA in humans is tissue-restricted, the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism. This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation.

Partner Proteins

KDM5B

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Guinea Pig: 100%; Human: 100%; Mouse: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

54kDa

References & Citations

Rauch, T., (2006) Cancer Res. 66 (16), 7939-7947

Shipping Conditions

Wet Ice

Protein Length

504

NCBI Gene Symbol

ONECUT2

NCBI GB Accession Number

ONECUT2

Host or Source

Rabbit

Protein Name

One cut domain family member 2

Nucleotide Accession Number

NM_004852

Peptide Sequence

TSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSNTYTTLTPLQPL

Frequently Asked Questions

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