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DHX16 Antibody - N-terminal region : HRP (ARP37711_P050-HRP)

Selected Variant

ARP37711_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

DEAH (Asp-Glu-Ala-His) box polypeptide 16

Gene Aliases

DBP2, PRP8, Prp2, DDX16, NMOAS, PRPF2, PRO2014

Gene ID

8449

Swiss Prot

O60231

Accession Number

NP_003578

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Goat, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human DHX16

Target

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked.

Partner Proteins

NUDCD1; UBC; GPKOW; SF3B2; DHX38; DGCR14; CSNK2A1; XAB2; HELQ; PYROXD1; NAA40; LSM2; MIF4GD; GON4L; WDR44; EHD2; LSM5; LSM6; GCC2; TCEA2; MTR; GSPT1; GABPB1; APP; COIL; SNRNP27; SNRNP40; SIRT7; MEGF10; Bud13; TADA2A; SRRM2; SRRM1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

DHX16 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 86%; Goat: 86%; Horse: 86%; Human: 100%; Mouse: 79%; Pig: 85%; Rabbit: 77%; Rat: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

115kDa

References & Citations

Beausoleil, S.A., et al., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135

Shipping Conditions

Wet Ice

Protein Length

1041

NCBI Gene Symbol

DHX16

NCBI GB Accession Number

DHX16

Host or Source

Rabbit

Protein Name

Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

Nucleotide Accession Number

NM_003587

Peptide Sequence

KYQLVLEEEETIEFVRATQLQGDEEPSAPPTSTQAQQKESIQAVRRSLPV

Price

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