Mafa Antibody - C-terminal region : HRP (ARP37614_P050-HRP)
Selected Variant
ARP37614_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
V-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
Gene Aliases
RIPE, RIPE3b1
Gene ID
378435
Swiss Prot
Q8CF90
Accession Number
NP_919331
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen is a synthetic peptide corresponding to a region of Mouse
Target
Mafa acts as a transcriptional factor. Mafa specifically binds the insulin enhancer element RIPE3b. Mafa cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Mafa regulates the insulin gene transcription. Mafa is involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Partner Proteins
Psme3
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 86%; Mouse: 100%; Rat: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
37kDa
Shipping Conditions
Wet Ice
Protein Length
359
NCBI Gene Symbol
MAFA
NCBI GB Accession Number
Mafa
Host or Source
Rabbit
Protein Name
Transcription factor MafA
Nucleotide Accession Number
NM_194350
Peptide Sequence
KLEVGRLAKERDLYKEKYEKLAGRGGPGGAGGAGFPREPSPAQAGPGAAK
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