Sra1 Antibody - N-terminal region : Biotin (ARP37345_P050-Biotin)
Selected Variant
ARP37345_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Steroid receptor RNA activator 1
Gene Aliases
Sra, Srap, Straa1, Strra1, AA959952
Gene ID
24068
Swiss Prot
Q80VJ2
Accession Number
NP_079567
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide corresponding to a region of Mouse
Target
Sra1 is a functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Sra1 also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2) .Sra1 enhances cellular proliferation and differentiation and promotes apoptosis in vivo. Sra1 may play a role in tumorigenesis.
Partner Proteins
CFTR; Traf6; Pus1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 93%; Mouse: 93%; Pig: 93%; Rabbit: 93%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
24kDa
Shipping Conditions
Wet Ice
Protein Length
220
NCBI Gene Symbol
SRA1
NCBI GB Accession Number
Sra1
Host or Source
Rabbit
Protein Name
Steroid receptor RNA activator 1
Nucleotide Accession Number
NM_025291
Peptide Sequence
MMRCPAGGAEVEMAELYVKPGNKERGWNDPPQFSYGLQTQTGGPKRTPLT
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