YAF2 Antibody - middle region: Biotin (ARP37341_P050-Biotin)
Product Specifications
Gene Name
YY1 associated factor 2
Gene Aliases
2810021M11Rik
Gene ID
67057
Swiss Prot
Q99LW6
Accession Number
NP_077151
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of mouse YAF2
Target
Yaf2 binds to MYC and inhibits MYC-mediated transactivation. Yaf2 also binds to MYCN and enhances MYCN-dependent transcriptional activation. Yaf2 increases calpain 2-mediated proteolysis of YY1 in vitro. Yaf2 is a component of the E2F6.com-1 complex, a repressive complex that methylates Lys-9 of histone H3, suggesting that it is involved in chromatin-remodeling.
Partner Proteins
Map3k1; Kdm2b; Rnf2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 80%; Dog: 80%; Guinea Pig: 80%; Horse: 80%; Human: 80%; Mouse: 100%; Rat: 80%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
20kDa
Shipping Conditions
Wet Ice
Protein Length
179
NCBI Gene Symbol
YAF2
Protein Name
YY1-associated factor 2
Nucleotide Accession Number
NM_024189
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