Taf1b Antibody - middle region : Biotin (ARP37290_P050-Biotin)

Product Specifications

Gene Name

TATA box binding protein (Tbp) -associated factor, RNA polymerase I, B

Gene Aliases

P6, p63, mTAFI, TAFI68, Tafi86, 4930408G01Rik, A230108M10Rik

Gene ID

21340

Swiss Prot

P97358

Accession Number

NP_065639

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of mouse Taf1b

Target

Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.

Partner Proteins

COPS2; Tbp; Taf1c; Taf1a; Rrn3; Tcf3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Mouse: 100%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.