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PUS1 Antibody - C-terminal region : Biotin (ARP37261_P050-Biotin)

Product Specifications

Gene Name

Pseudouridine synthase 1

Gene Aliases

MPU, MPUS1, mPus1p, A730013B20Rik

Gene ID

56361

Swiss Prot

Q791J1

Accession Number

NP_001020733

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The immunogen is a synthetic peptide corresponding to a region of Mouse

Target

Pus1 converts specific uridines to PSI in a number of tRNA substrates. Pus1 acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Pus1 is involved in regulation of nuclear receptor activity possibly through pseudouridylation of SRA1 RNA.

Partner Proteins

Rarg; Sra1; Rarb

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 92%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

48kDa

References & Citations

Zhao, X., et al., (2004) Mol. Cell 15 (4), 549-558

Shipping Conditions

Wet Ice

Protein Length

423

NCBI Gene Symbol

PUS1

NCBI GB Accession Number

PUS1

Host or Source

Rabbit

Protein Name

TRNA pseudouridine synthase A, mitochondrial

Nucleotide Accession Number

NM_001025562

Peptide Sequence

PTIVSTERDERSMAQWLNTLPIHNFSGTALGAADTGAKVPSSLEGSEGDG

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