PUS1 Antibody - C-terminal region : HRP (ARP37261_P050-HRP)
Selected Variant
ARP37261_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Pseudouridine synthase 1
Gene Aliases
MPU, MPUS1, mPus1p, A730013B20Rik
Gene ID
56361
Swiss Prot
Q791J1
Accession Number
NP_001020733
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen is a synthetic peptide corresponding to a region of Mouse
Target
Pus1 converts specific uridines to PSI in a number of tRNA substrates. Pus1 acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Pus1 is involved in regulation of nuclear receptor activity possibly through pseudouridylation of SRA1 RNA.
Partner Proteins
Rarg; Sra1; Rarb
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 92%; Mouse: 100%; Rat: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
48kDa
References & Citations
Zhao, X., et al., (2004) Mol. Cell 15 (4), 549-558
Shipping Conditions
Wet Ice
Protein Length
423
NCBI Gene Symbol
PUS1
NCBI GB Accession Number
PUS1
Host or Source
Rabbit
Protein Name
TRNA pseudouridine synthase A, mitochondrial
Nucleotide Accession Number
NM_001025562
Peptide Sequence
PTIVSTERDERSMAQWLNTLPIHNFSGTALGAADTGAKVPSSLEGSEGDG
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